The road less traveled: transport of Legionella to the endoplasmic reticulum

نویسندگان

  • Craig R. Roy
  • Lewis G. Tilney
چکیده

Phagosomes containing the bacterial pathogen Legionella pneumophila are transported to the ER after macrophage internalization. To modulate phagosome transport, Legionella use a specialized secretion system that injects bacterial proteins into eukaryotic cells. This review will focus on recent studies that have identified bacterial proteins and host processes that play a concerted role in transporting Legionella to the ER.

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تاریخ انتشار 2002